FBXL18 FISH Probe
The FBXL18 FISH probe is designed to hybridize to the FBXL18 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| FBXL18-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| FBXL18-20-RE | 20 (40 μL) | 200 μL |  |
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| FBXL18-20-GO | 20 (40 μL) | 200 μL |  |
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| FBXL18-20-GR | 20 (40 μL) | 200 μL |  |
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| FBXL18-20-AQ | 20 (40 μL) | 200 μL |  |
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| FBXL18-20-DIG | 20 (40 μL) | 200 μL |  |
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| FBXL18-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7, a protein that induces mitotic arrest, by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. [provided by RefSeq, Mar 2016]
Gene Details
Gene Symbol: FBXL18
Gene Name: F-box And Leucine Rich Repeat Protein 18
Chromosome: CHR7: 5515427-5553399
Locus: 7p22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: FBXL18 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FBXL18-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping