EMP-2 FISH Probe
The EMP-2 FISH probe is designed to hybridize to the EMP-2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EMP2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| EMP2-20-RE | 20 (40 μL) | 200 μL |  |
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| EMP2-20-GO | 20 (40 μL) | 200 μL |  |
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| EMP2-20-GR | 20 (40 μL) | 200 μL |  |
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| EMP2-20-AQ | 20 (40 μL) | 200 μL |  |
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| EMP2-20-DIG | 20 (40 μL) | 200 μL |  |
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| EMP2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a tetraspan protein of the PMP22/EMP family. The encoded protein regulates cell membrane composition. It has been associated with various functions including endocytosis, cell signaling, cell proliferation, cell migration, cell adhesion, cell death, cholesterol homeostasis, urinary albumin excretion, and embryo implantation. It is known to negatively regulate caveolin-1, a scaffolding protein which is the main component of the caveolae plasma membrane invaginations found in most cell types. Through activation of PTK2 it positively regulates vascular endothelial growth factor A. It also modulates the function of specific integrin isomers in the plasma membrane. Up-regulation of this gene has been linked to cancer progression in multiple different tissues. Mutations in this gene have been associated with nephrotic syndrome type 10 (NPHS10). [provided by RefSeq, Mar 2015]
Gene Details
Gene Symbol: EMP2
Gene Name: Epithelial Membrane Protein 2
Chromosome: CHR16: 10622278-10674539
Locus: 16p13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EMP-2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EMP2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping