E130307D12 FISH Probe
The E130307D12 FISH probe is designed to hybridize to the E130307D12 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SAFB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SAFB-20-RE | 20 (40 μL) | 200 μL |  |
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| SAFB-20-GO | 20 (40 μL) | 200 μL |  |
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| SAFB-20-GR | 20 (40 μL) | 200 μL |  |
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| SAFB-20-AQ | 20 (40 μL) | 200 μL |  |
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| SAFB-20-DIG | 20 (40 μL) | 200 μL |  |
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| SAFB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]
Gene Details
Gene Symbol: SAFB
Gene Name: Scaffold Attachment Factor B
Chromosome: CHR19: 5623045-5668489
Locus: 19p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: E130307D12 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SAFB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping