DYT23 FISH Probe
The DYT23 FISH probe is designed to hybridize to the DYT23 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANO3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ANO3-20-RE | 20 (40 μL) | 200 μL |  |
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| ANO3-20-GO | 20 (40 μL) | 200 μL |  |
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| ANO3-20-GR | 20 (40 μL) | 200 μL |  |
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| ANO3-20-AQ | 20 (40 μL) | 200 μL |  |
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| ANO3-20-DIG | 20 (40 μL) | 200 μL |  |
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| ANO3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: ANO3
Gene Name: Anoctamin 3
Chromosome: CHR11: 26353677-26684836
Locus: 11p14.3-p14.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DYT23 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ANO3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping