DSEP FISH Probe
The DSEP FISH probe is designed to hybridize to the DSEP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DSE-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DSE-20-RE | 20 (40 μL) | 200 μL |  |
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| DSE-20-GO | 20 (40 μL) | 200 μL |  |
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| DSE-20-GR | 20 (40 μL) | 200 μL |  |
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| DSE-20-AQ | 20 (40 μL) | 200 μL |  |
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| DSE-20-DIG | 20 (40 μL) | 200 μL |  |
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| DSE-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a tumor-rejection antigen. It is localized to the endoplasmic reticulum and functions to convert D-glucuronic acid to L-iduronic acid during the biosynthesis of dermatan sulfate. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. Mutations in this gene cause inmusculocontractural Ehlers-Danlos syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 9, and a paralogous gene exists on chromosome 18. [provided by RefSeq, Apr 2016]
Gene Details
Gene Symbol: DSE
Gene Name: Dermatan Sulfate Epimerase
Chromosome: CHR6: 116601282-116759442
Locus: 6q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DSEP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DSE-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping