DSC1 FISH Probe
The DSC1 FISH probe is designed to hybridize to the DSC1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DSC1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| DSC1-20-RE | 20 (40 μL) | 200 μL |  |
|
| DSC1-20-GO | 20 (40 μL) | 200 μL |  |
|
| DSC1-20-GR | 20 (40 μL) | 200 μL |  |
|
| DSC1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| DSC1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| DSC1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. A subtype of IgA pemphigus, a life-threatening autoimmune disease, is characterized by the presence of autoantibodies that target the encoded protein. The desmosomal family members are arranged in two clusters on chromosome 18. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protein. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: DSC1
Gene Name: Desmocollin 1
Chromosome: CHR18: 28709213-28742819
Locus: 18q12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: DSC1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DSC1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping