DRE1 FISH Probe
The DRE1 FISH probe is designed to hybridize to the DRE1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KLHL24-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| KLHL24-20-RE | 20 (40 μL) | 200 μL |  |
|
| KLHL24-20-GO | 20 (40 μL) | 200 μL |  |
|
| KLHL24-20-GR | 20 (40 μL) | 200 μL |  |
|
| KLHL24-20-AQ | 20 (40 μL) | 200 μL |  |
|
| KLHL24-20-DIG | 20 (40 μL) | 200 μL |  |
|
| KLHL24-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a ubiquitin ligase substrate receptor and is regulated by autoubiquitination. Variations in the translation initiation codon of this gene have been found, which result in an N-terminally truncated but more stable protein due to loss of the autoubiquitination function. The more stable mutant protein causes an increased ubiquitin and degradation of keratin 14, which leads to skin fragility and the potentially life-threatening disease epidermolysis bullosa. The encoded protein is also involved in the regulation of kainate receptors. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: KLHL24
Gene Name: Kelch Like Family Member 24
Chromosome: CHR3: 183353410-183402304
Locus: 3q27.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: DRE1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KLHL24-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping