DPM1 FISH Probe
The DPM1 FISH probe is designed to hybridize to the DPM1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DPM1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DPM1-20-RE | 20 (40 μL) | 200 μL |  |
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| DPM1-20-GO | 20 (40 μL) | 200 μL |  |
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| DPM1-20-GR | 20 (40 μL) | 200 μL |  |
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| DPM1-20-AQ | 20 (40 μL) | 200 μL |  |
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| DPM1-20-DIG | 20 (40 μL) | 200 μL |  |
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| DPM1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. Mutations in this gene are associated with congenital disorder of glycosylation type Ie. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: DPM1
Gene Name: Dolichyl-phosphate Mannosyltransferase Subunit 1, Catalytic
Chromosome: CHR20: 49551404-49575060
Locus: 20q13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DPM1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DPM1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping