SEARCH OUR PRODUCT CATALOG

DMK FISH Probe

The DMK FISH probe is designed to hybridize to the DMK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DMPK-20-OR  (Standard Design) 20 (40 μL) 200 μL
DMPK-20-RE 20 (40 μL) 200 μL
DMPK-20-GO 20 (40 μL) 200 μL
DMPK-20-GR 20 (40 μL) 200 μL
DMPK-20-AQ 20 (40 μL) 200 μL
DMPK-20-DIG 20 (40 μL) 200 μL
DMPK-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-38 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2016]

Gene Details

Gene Symbol: DMPK

Gene Name: DM1 Protein Kinase

Chromosome: CHR19: 46272975-46285815

Locus: 19q13.32

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: DMK FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: DMPK-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping