DKIR FISH Probe
The DKIR FISH probe is designed to hybridize to the DKIR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KLHL12-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KLHL12-20-RE | 20 (40 μL) | 200 μL |  |
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| KLHL12-20-GO | 20 (40 μL) | 200 μL |  |
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| KLHL12-20-GR | 20 (40 μL) | 200 μL |  |
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| KLHL12-20-AQ | 20 (40 μL) | 200 μL |  |
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| KLHL12-20-DIG | 20 (40 μL) | 200 μL |  |
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| KLHL12-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Details
Gene Symbol: KLHL12
Gene Name: Kelch Like Family Member 12
Chromosome: CHR1: 202860229-202896371
Locus: 1q32.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: DKIR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KLHL12-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping