DKCX FISH Probe
The DKCX FISH probe is designed to hybridize to the DKCX gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DKC1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DKC1-20-RE | 20 (40 μL) | 200 μL |  |
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| DKC1-20-GO | 20 (40 μL) | 200 μL |  |
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| DKC1-20-GR | 20 (40 μL) | 200 μL |  |
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| DKC1-20-AQ | 20 (40 μL) | 200 μL |  |
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| DKC1-20-DIG | 20 (40 μL) | 200 μL |  |
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| DKC1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Details
Gene Symbol: DKC1
Gene Name: Dyskerin Pseudouridine Synthase 1
Chromosome: CHRX: 153991030-154005964
Locus: Xq28
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: DKCX FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DKC1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping