DFNB1A FISH Probe
The DFNB1A FISH probe is designed to hybridize to the DFNB1A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GJB2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GJB2-20-RE | 20 (40 μL) | 200 μL |  |
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| GJB2-20-GO | 20 (40 μL) | 200 μL |  |
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| GJB2-20-GR | 20 (40 μL) | 200 μL |  |
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| GJB2-20-AQ | 20 (40 μL) | 200 μL |  |
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| GJB2-20-DIG | 20 (40 μL) | 200 μL |  |
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| GJB2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq, Oct 2008]
Gene Details
Gene Symbol: GJB2
Gene Name: Gap Junction Protein Beta 2
Chromosome: CHR13: 20761603-20767114
Locus: 13q12.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DFNB1A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GJB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping