DDIT3 FISH Probe
The DDIT3 FISH probe is designed to hybridize to the DDIT3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DDIT3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DDIT3-20-RE | 20 (40 μL) | 200 μL |  |
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| DDIT3-20-GO | 20 (40 μL) | 200 μL |  |
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| DDIT3-20-GR | 20 (40 μL) | 200 μL |  |
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| DDIT3-20-AQ | 20 (40 μL) | 200 μL |  |
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| DDIT3-20-DIG | 20 (40 μL) | 200 μL |  |
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| DDIT3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
Gene Details
Gene Symbol: DDIT3
Gene Name: DNA Damage Inducible Transcript 3
Chromosome: CHR12: 57910370-57914300
Locus: 12q13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DDIT3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DDIT3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping