DCC FISH Probe
The DCC FISH probe is designed to hybridize to the DCC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DCC-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DCC-20-RE | 20 (40 μL) | 200 μL |  |
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| DCC-20-GO | 20 (40 μL) | 200 μL |  |
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| DCC-20-GR | 20 (40 μL) | 200 μL |  |
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| DCC-20-AQ | 20 (40 μL) | 200 μL |  |
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| DCC-20-DIG | 20 (40 μL) | 200 μL |  |
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| DCC-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009]
Gene Details
Gene Symbol: DCC
Gene Name: DCC Netrin 1 Receptor
Chromosome: CHR18: 49866541-51062273
Locus: 18q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: DCC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DCC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping