DBMT1 FISH Probe
The DBMT1 FISH probe is designed to hybridize to the DBMT1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DMBT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DMBT1-20-RE | 20 (40 μL) | 200 μL |  |
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| DMBT1-20-GO | 20 (40 μL) | 200 μL |  |
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| DMBT1-20-GR | 20 (40 μL) | 200 μL |  |
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| DMBT1-20-AQ | 20 (40 μL) | 200 μL |  |
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| DMBT1-20-DIG | 20 (40 μL) | 200 μL |  |
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| DMBT1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016]
Gene Details
Gene Symbol: DMBT1
Gene Name: Deleted In Malignant Brain Tumors 1
Chromosome: CHR10: 124320180-124403252
Locus: 10q26.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DBMT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DMBT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping