DBM FISH Probe
The DBM FISH probe is designed to hybridize to the DBM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DBH-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DBH-20-RE | 20 (40 μL) | 200 μL |  |
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| DBH-20-GO | 20 (40 μL) | 200 μL |  |
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| DBH-20-GR | 20 (40 μL) | 200 μL |  |
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| DBH-20-AQ | 20 (40 μL) | 200 μL |  |
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| DBH-20-DIG | 20 (40 μL) | 200 μL |  |
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| DBH-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. The encoded protein, expressed in neuroscretory vesicles and chromaffin granules of the adrenal medulla, catalyzes the conversion of dopamine to norepinephrine, which functions as both a hormone and as the main neurotransmitter of the sympathetic nervous system. The enzyme encoded by this gene exists exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide. Mutations in this gene cause dopamine beta-hydroxylate deficiency in human patients, characterized by deficits in autonomic and cardiovascular function, including hypotension and ptosis. Polymorphisms in this gene may play a role in a variety of psychiatric disorders. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: DBH
Gene Name: Dopamine Beta-hydroxylase
Chromosome: CHR9: 136501484-136524466
Locus: 9q34.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DBM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DBH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping