D8 FISH Probe
The D8 FISH probe is designed to hybridize to the D8 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UBA7-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| UBA7-20-RE | 20 (40 μL) | 200 μL |  |
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| UBA7-20-GO | 20 (40 μL) | 200 μL |  |
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| UBA7-20-GR | 20 (40 μL) | 200 μL |  |
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| UBA7-20-AQ | 20 (40 μL) | 200 μL |  |
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| UBA7-20-DIG | 20 (40 μL) | 200 μL |  |
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| UBA7-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: UBA7
Gene Name: Ubiquitin Like Modifier Activating Enzyme 7
Chromosome: CHR3: 49842637-49851391
Locus: 3p21.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: D8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UBA7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping