CYP27B1 FISH Probe
The CYP27B1 FISH probe is designed to hybridize to the CYP27B1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP27B1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CYP27B1-20-RE | 20 (40 μL) | 200 μL |  |
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| CYP27B1-20-GO | 20 (40 μL) | 200 μL |  |
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| CYP27B1-20-GR | 20 (40 μL) | 200 μL |  |
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| CYP27B1-20-AQ | 20 (40 μL) | 200 μL |  |
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| CYP27B1-20-DIG | 20 (40 μL) | 200 μL |  |
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| CYP27B1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CYP27B1
Gene Name: Cytochrome P450 Family 27 Subfamily B Member 1
Chromosome: CHR12: 58156116-58160976
Locus: 12q14.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CYP27B1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CYP27B1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping