COL1A1 FISH Probe
The COL1A1 FISH probe is designed to hybridize to the COL1A1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| COL1A1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| COL1A1-20-RE | 20 (40 μL) | 200 μL |  |
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| COL1A1-20-GO | 20 (40 μL) | 200 μL |  |
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| COL1A1-20-GR | 20 (40 μL) | 200 μL |  |
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| COL1A1-20-AQ | 20 (40 μL) | 200 μL |  |
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| COL1A1-20-DIG | 20 (40 μL) | 200 μL |  |
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| COL1A1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
Gene Details
Gene Symbol: COL1A1
Gene Name: Collagen Type I Alpha 1 Chain
Chromosome: CHR17: 48261456-48279000
Locus: 17q21.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: COL1A1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: COL1A1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping