CMT1F FISH Probe
The CMT1F FISH probe is designed to hybridize to the CMT1F gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NEFL-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NEFL-20-RE | 20 (40 μL) | 200 μL |  |
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| NEFL-20-GO | 20 (40 μL) | 200 μL |  |
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| NEFL-20-GR | 20 (40 μL) | 200 μL |  |
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| NEFL-20-AQ | 20 (40 μL) | 200 μL |  |
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| NEFL-20-DIG | 20 (40 μL) | 200 μL |  |
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| NEFL-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
Gene Details
Gene Symbol: NEFL
Gene Name: Neurofilament Light
Chromosome: CHR8: 24808468-24814131
Locus: 8p21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CMT1F FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NEFL-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping