CLICK-II FISH Probe
The CLICK-II FISH probe is designed to hybridize to the CLICK-II gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DCLK2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DCLK2-20-RE | 20 (40 μL) | 200 μL |  |
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| DCLK2-20-GO | 20 (40 μL) | 200 μL |  |
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| DCLK2-20-GR | 20 (40 μL) | 200 μL |  |
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| DCLK2-20-AQ | 20 (40 μL) | 200 μL |  |
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| DCLK2-20-DIG | 20 (40 μL) | 200 μL |  |
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| DCLK2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Sep 2010]
Gene Details
Gene Symbol: DCLK2
Gene Name: Doublecortin Like Kinase 2
Chromosome: CHR4: 150999425-151178608
Locus: 4q31.23-q31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CLICK-II FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DCLK2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping