CK-6A FISH Probe
The CK-6A FISH probe is designed to hybridize to the CK-6A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KRT6A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KRT6A-20-RE | 20 (40 μL) | 200 μL |  |
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| KRT6A-20-GO | 20 (40 μL) | 200 μL |  |
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| KRT6A-20-GR | 20 (40 μL) | 200 μL |  |
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| KRT6A-20-AQ | 20 (40 μL) | 200 μL |  |
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| KRT6A-20-DIG | 20 (40 μL) | 200 μL |  |
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| KRT6A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Oct 2014]
Gene Details
Gene Symbol: KRT6A
Gene Name: Keratin 6A
Chromosome: CHR12: 52880957-52887181
Locus: 12q13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CK-6A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KRT6A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping