CILP FISH Probe
The CILP FISH probe is designed to hybridize to the CILP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CILP-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
CILP-20-RE | 20 (40 μL) | 200 μL | ||
CILP-20-GO | 20 (40 μL) | 200 μL | ||
CILP-20-GR | 20 (40 μL) | 200 μL | ||
CILP-20-AQ | 20 (40 μL) | 200 μL | ||
CILP-20-DIG | 20 (40 μL) | 200 μL | ||
CILP-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
Major alterations in the composition of the cartilage extracellular matrix occur in joint disease, such as osteoarthrosis. This gene encodes the cartilage intermediate layer protein (CILP), which increases in early osteoarthrosis cartilage. The encoded protein was thought to encode a protein precursor for two different proteins; an N-terminal CILP and a C-terminal homolog of NTPPHase, however, later studies identified no nucleotide pyrophosphatase phosphodiesterase (NPP) activity. The full-length and the N-terminal domain of this protein was shown to function as an IGF-1 antagonist. An allelic variant of this gene has been associated with lumbar disc disease. [provided by RefSeq, Sep 2010]
Gene Details
Gene Symbol: CILP
Gene Name: Cartilage Intermediate Layer Protein
Chromosome: CHR15: 65488336-65503840
Locus: 15q22.31
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CILP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CILP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping