CHTD2 FISH Probe
The CHTD2 FISH probe is designed to hybridize to the CHTD2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TAB2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TAB2-20-RE | 20 (40 μL) | 200 μL |  |
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| TAB2-20-GO | 20 (40 μL) | 200 μL |  |
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| TAB2-20-GR | 20 (40 μL) | 200 μL |  |
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| TAB2-20-AQ | 20 (40 μL) | 200 μL |  |
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| TAB2-20-DIG | 20 (40 μL) | 200 μL |  |
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| TAB2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Details
Gene Symbol: TAB2
Gene Name: TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2
Chromosome: CHR6: 149639435-149732747
Locus: 6q25.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CHTD2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TAB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping