CHRNG FISH Probe
The CHRNG FISH probe is designed to hybridize to the CHRNG gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHRNG-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CHRNG-20-RE | 20 (40 μL) | 200 μL |  |
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| CHRNG-20-GO | 20 (40 μL) | 200 μL |  |
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| CHRNG-20-GR | 20 (40 μL) | 200 μL |  |
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| CHRNG-20-AQ | 20 (40 μL) | 200 μL |  |
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| CHRNG-20-DIG | 20 (40 μL) | 200 μL |  |
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| CHRNG-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.[provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: CHRNG
Gene Name: Cholinergic Receptor Nicotinic Gamma Subunit
Chromosome: CHR2: 233404436-233411038
Locus: 2q37.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CHRNG FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CHRNG-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping