CHRNB4 FISH Probe
The CHRNB4 FISH probe is designed to hybridize to the CHRNB4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHRNB4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| CHRNB4-20-RE | 20 (40 μL) | 200 μL |  |
|
| CHRNB4-20-GO | 20 (40 μL) | 200 μL |  |
|
| CHRNB4-20-GR | 20 (40 μL) | 200 μL |  |
|
| CHRNB4-20-AQ | 20 (40 μL) | 200 μL |  |
|
| CHRNB4-20-DIG | 20 (40 μL) | 200 μL |  |
|
| CHRNB4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is found within a conserved gene cluster and encodes one of the beta subunits of the nicotinic acetylcholine receptor (nAChRs) superfamily which form ligand-gated ion channels with a central pore that forms a cation channel. Neuronal nAChRs are pentameric structures that can be either homomeric or heteromeric, with heteromeric structures containing both alpha and beta subunits. Each subunit contains an extracellular amino terminus and four transmembrane domains. Nicotine is one of the agonists that binds to the receptor. Variants in this gene have been associated with nicotine dependence and lung cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2017]
Gene Details
Gene Symbol: CHRNB4
Gene Name: Cholinergic Receptor Nicotinic Beta 4 Subunit
Chromosome: CHR15: 78916635-78933587
Locus: 15q25.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: CHRNB4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CHRNB4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping