CG5229-PA FISH Probe
The CG5229-PA FISH probe is designed to hybridize to the CG5229-PA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CHM-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CHM-20-RE | 20 (40 μL) | 200 μL |  |
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| CHM-20-GO | 20 (40 μL) | 200 μL |  |
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| CHM-20-GR | 20 (40 μL) | 200 μL |  |
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| CHM-20-AQ | 20 (40 μL) | 200 μL |  |
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| CHM-20-DIG | 20 (40 μL) | 200 μL |  |
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| CHM-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
Gene Details
Gene Symbol: CHM
Gene Name: CHM, Rab Escort Protein 1
Chromosome: CHRX: 85116184-85302566
Locus: Xq21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CG5229-PA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CHM-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping