CFL FISH Probe
The CFL FISH probe is designed to hybridize to the CFL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CFL1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CFL1-20-RE | 20 (40 μL) | 200 μL |  |
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| CFL1-20-GO | 20 (40 μL) | 200 μL |  |
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| CFL1-20-GR | 20 (40 μL) | 200 μL |  |
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| CFL1-20-AQ | 20 (40 μL) | 200 μL |  |
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| CFL1-20-DIG | 20 (40 μL) | 200 μL |  |
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| CFL1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
Gene Details
Gene Symbol: CFL1
Gene Name: Cofilin 1
Chromosome: CHR11: 65622284-65625804
Locus: 11q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CFL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CFL1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping