CENP-33 FISH Probe
The CENP-33 FISH probe is designed to hybridize to the CENP-33 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LRWD1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LRWD1-20-RE | 20 (40 μL) | 200 μL |  |
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| LRWD1-20-GO | 20 (40 μL) | 200 μL |  |
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| LRWD1-20-GR | 20 (40 μL) | 200 μL |  |
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| LRWD1-20-AQ | 20 (40 μL) | 200 μL |  |
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| LRWD1-20-DIG | 20 (40 μL) | 200 μL |  |
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| LRWD1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
Gene Details
Gene Symbol: LRWD1
Gene Name: Leucine Rich Repeats And WD Repeat Domain Containing 1
Chromosome: CHR7: 102105389-102113612
Locus: 7q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CENP-33 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LRWD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping