CDC42 FISH Probe
The CDC42 FISH probe is designed to hybridize to the CDC42 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDC42-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CDC42-20-RE | 20 (40 μL) | 200 μL |  |
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| CDC42-20-GO | 20 (40 μL) | 200 μL |  |
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| CDC42-20-GR | 20 (40 μL) | 200 μL |  |
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| CDC42-20-AQ | 20 (40 μL) | 200 μL |  |
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| CDC42-20-DIG | 20 (40 μL) | 200 μL |  |
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| CDC42-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]
Gene Details
Gene Symbol: CDC42
Gene Name: Cell Division Cycle 42
Chromosome: CHR1: 22379119-22419436
Locus: 1p36.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDC42 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDC42-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping