CDC27 FISH Probe
The CDC27 FISH probe is designed to hybridize to the CDC27 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDC27-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CDC27-20-RE | 20 (40 μL) | 200 μL |  |
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| CDC27-20-GO | 20 (40 μL) | 200 μL |  |
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| CDC27-20-GR | 20 (40 μL) | 200 μL |  |
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| CDC27-20-AQ | 20 (40 μL) | 200 μL |  |
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| CDC27-20-DIG | 20 (40 μL) | 200 μL |  |
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| CDC27-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of the anaphase-promoting complex (APC), which is composed of eight protein subunits and is highly conserved in eukaryotic cells. This complex catalyzes the formation of cyclin B-ubiquitin conjugate, which is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. The protein encoded by this gene and three other members of the APC complex contain tetratricopeptide (TPR) repeats, which are important for protein-protein interactions. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and it may thus be involved in controlling the timing of mitosis. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 22 and Y. [provided by RefSeq, May 2014]
Gene Details
Gene Symbol: CDC27
Gene Name: Cell Division Cycle 27
Chromosome: CHR17: 45195310-45266665
Locus: 17q21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CDC27 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CDC27-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping