CD8B FISH Probe
The CD8B FISH probe is designed to hybridize to the CD8B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CD8B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CD8B-20-RE | 20 (40 μL) | 200 μL |  |
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| CD8B-20-GO | 20 (40 μL) | 200 μL |  |
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| CD8B-20-GR | 20 (40 μL) | 200 μL |  |
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| CD8B-20-AQ | 20 (40 μL) | 200 μL |  |
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| CD8B-20-DIG | 20 (40 μL) | 200 μL |  |
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| CD8B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
Gene Details
Gene Symbol: CD8B
Gene Name: CD8b Molecule
Chromosome: CHR2: 87042459-87089047
Locus: 2p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CD8B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CD8B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping