CD40 FISH Probe
The CD40 FISH probe is designed to hybridize to the CD40 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CD40-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CD40-20-RE | 20 (40 μL) | 200 μL |  |
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| CD40-20-GO | 20 (40 μL) | 200 μL |  |
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| CD40-20-GR | 20 (40 μL) | 200 μL |  |
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| CD40-20-AQ | 20 (40 μL) | 200 μL |  |
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| CD40-20-DIG | 20 (40 μL) | 200 μL |  |
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| CD40-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2014]
Gene Details
Gene Symbol: CD40
Gene Name: CD40 Molecule
Chromosome: CHR20: 44746905-44758384
Locus: 20q13.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CD40 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CD40-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping