CD142 FISH Probe
The CD142 FISH probe is designed to hybridize to the CD142 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
F3-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
F3-20-RE | 20 (40 μL) | 200 μL | ||
F3-20-GO | 20 (40 μL) | 200 μL | ||
F3-20-GR | 20 (40 μL) | 200 μL | ||
F3-20-AQ | 20 (40 μL) | 200 μL | ||
F3-20-DIG | 20 (40 μL) | 200 μL | ||
F3-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Gene Details
Gene Symbol: F3
Gene Name: Coagulation Factor III, Tissue Factor
Chromosome: CHR1: 94994731-95007413
Locus: 1p21.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CD142 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: F3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping