CAMLG FISH Probe
The CAMLG FISH probe is designed to hybridize to the CAMLG gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CAMLG-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
CAMLG-20-RE | 20 (40 μL) | 200 μL | ||
CAMLG-20-GO | 20 (40 μL) | 200 μL | ||
CAMLG-20-GR | 20 (40 μL) | 200 μL | ||
CAMLG-20-AQ | 20 (40 μL) | 200 μL | ||
CAMLG-20-DIG | 20 (40 μL) | 200 μL | ||
CAMLG-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CAMLG
Gene Name: Calcium Modulating Ligand
Chromosome: CHR5: 134074169-134087850
Locus: 5q31.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CAMLG FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CAMLG-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping