CADASIL1 FISH Probe
The CADASIL1 FISH probe is designed to hybridize to the CADASIL1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NOTCH3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NOTCH3-20-RE | 20 (40 μL) | 200 μL |  |
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| NOTCH3-20-GO | 20 (40 μL) | 200 μL |  |
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| NOTCH3-20-GR | 20 (40 μL) | 200 μL |  |
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| NOTCH3-20-AQ | 20 (40 μL) | 200 μL |  |
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| NOTCH3-20-DIG | 20 (40 μL) | 200 μL |  |
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| NOTCH3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: NOTCH3
Gene Name: Notch 3
Chromosome: CHR19: 15270443-15311792
Locus: 19p13.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CADASIL1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NOTCH3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping