CAD FISH Probe
The CAD FISH probe is designed to hybridize to the CAD gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CAD-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CAD-20-RE | 20 (40 μL) | 200 μL |  |
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| CAD-20-GO | 20 (40 μL) | 200 μL |  |
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| CAD-20-GR | 20 (40 μL) | 200 μL |  |
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| CAD-20-AQ | 20 (40 μL) | 200 μL |  |
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| CAD-20-DIG | 20 (40 μL) | 200 μL |  |
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| CAD-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Gene Details
Gene Symbol: CAD
Gene Name: Carbamoyl-phosphate Synthetase 2, Aspartate Transcarbamylase, And Dihydroorotase
Chromosome: CHR2: 27440257-27466654
Locus: 2p23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CAD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CAD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping