C85531 FISH Probe
The C85531 FISH probe is designed to hybridize to the C85531 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
LITAF-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
LITAF-20-RE | 20 (40 μL) | 200 μL | ||
LITAF-20-GO | 20 (40 μL) | 200 μL | ||
LITAF-20-GR | 20 (40 μL) | 200 μL | ||
LITAF-20-AQ | 20 (40 μL) | 200 μL | ||
LITAF-20-DIG | 20 (40 μL) | 200 μL | ||
LITAF-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2014]
Gene Details
Gene Symbol: LITAF
Gene Name: Lipopolysaccharide Induced TNF Factor
Chromosome: CHR16: 11641577-11681322
Locus: 16p13.13
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: C85531 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LITAF-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping