C7 FISH Probe
The C7 FISH probe is designed to hybridize to the C7 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| C7-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| C7-20-RE | 20 (40 μL) | 200 μL |  |
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| C7-20-GO | 20 (40 μL) | 200 μL |  |
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| C7-20-GR | 20 (40 μL) | 200 μL |  |
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| C7-20-AQ | 20 (40 μL) | 200 μL |  |
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| C7-20-DIG | 20 (40 μL) | 200 μL |  |
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| C7-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a serum glycoprotein that forms a membrane attack complex together with complement components C5b, C6, C8, and C9 as part of the terminal complement pathway of the innate immune system. The protein encoded by this gene contains a cholesterol-dependent cytolysin/membrane attack complex/perforin-like (CDC/MACPF) domain and belongs to a large family of structurally related molecules that form pores involved in host immunity and bacterial pathogenesis. This protein initiates membrane attack complex formation by binding the C5b-C6 subcomplex and inserts into the phospholipid bilayer, serving as a membrane anchor. Mutations in this gene are associated with a rare disorder called C7 deficiency. [provided by RefSeq, Nov 2016]
Gene Details
Gene Symbol: C7
Gene Name: Complement C7
Chromosome: CHR5: 40909598-40983042
Locus: 5p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: C7 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: C7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping