C4BPB FISH Probe
The C4BPB FISH probe is designed to hybridize to the C4BPB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| C4BPB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| C4BPB-20-RE | 20 (40 μL) | 200 μL |  |
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| C4BPB-20-GO | 20 (40 μL) | 200 μL |  |
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| C4BPB-20-GR | 20 (40 μL) | 200 μL |  |
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| C4BPB-20-AQ | 20 (40 μL) | 200 μL |  |
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| C4BPB-20-DIG | 20 (40 μL) | 200 μL |  |
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| C4BPB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: C4BPB
Gene Name: Complement Component 4 Binding Protein Beta
Chromosome: CHR1: 207262211-207273337
Locus: 1q32.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: C4BPB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: C4BPB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping