BTL-II FISH Probe
The BTL-II FISH probe is designed to hybridize to the BTL-II gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BTNL2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BTNL2-20-RE | 20 (40 μL) | 200 μL |  |
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| BTNL2-20-GO | 20 (40 μL) | 200 μL |  |
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| BTNL2-20-GR | 20 (40 μL) | 200 μL |  |
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| BTNL2-20-AQ | 20 (40 μL) | 200 μL |  |
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| BTNL2-20-DIG | 20 (40 μL) | 200 μL |  |
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| BTNL2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer. [provided by RefSeq, May 2017]
Gene Details
Gene Symbol: BTNL2
Gene Name: Butyrophilin Like 2
Chromosome: CHR6_mann_hap4: 3705348-3717760
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BTL-II FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BTNL2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping