BRAT1 FISH Probe
The BRAT1 FISH probe is designed to hybridize to the BRAT1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| BRAT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| BRAT1-20-RE | 20 (40 μL) | 200 μL |  |
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| BRAT1-20-GO | 20 (40 μL) | 200 μL |  |
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| BRAT1-20-GR | 20 (40 μL) | 200 μL |  |
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| BRAT1-20-AQ | 20 (40 μL) | 200 μL |  |
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| BRAT1-20-DIG | 20 (40 μL) | 200 μL |  |
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| BRAT1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012]
Gene Details
Gene Symbol: BRAT1
Gene Name: BRCA1 Associated ATM Activator 1
Chromosome: CHR7: 2577443-2595392
Locus: 7p22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BRAT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: BRAT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping