BHLHB2 FISH Probe
The BHLHB2 FISH probe is designed to hybridize to the BHLHB2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TMEM2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TMEM2-20-RE | 20 (40 μL) | 200 μL |  |
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| TMEM2-20-GO | 20 (40 μL) | 200 μL |  |
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| TMEM2-20-GR | 20 (40 μL) | 200 μL |  |
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| TMEM2-20-AQ | 20 (40 μL) | 200 μL |  |
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| TMEM2-20-DIG | 20 (40 μL) | 200 μL |  |
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| TMEM2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a type II transmembrane protein that belongs to the interferon-induced transmembrane (IFITM) protein superfamily. The encoded protein functions as a cell surface hyaluronidase that cleaves extracellular high molecular weight hyaluronan into intermediate size fragments before internalization and degradation in the lysosome. It also has an interferon-mediated antiviral function in humans through activation of the JAK STAT signaling pathway. The activation of this gene by transcription factor SOX4 in breast cancer cells has been shown to mediate the pathological effects of SOX4 on cancer progression. Naturally occurring mutations in this gene are associated with autosomal recessive non-syndromic hearing loss. [provided by RefSeq, Mar 2017]
Gene Details
Gene Symbol: TMEM2
Gene Name: Transmembrane Protein 2
Chromosome: CHR9: 74298281-74383800
Locus: 9q21.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BHLHB2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TMEM2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping