BG:DS00004.13 FISH Probe
The BG:DS00004.13 FISH probe is designed to hybridize to the BG:DS00004.13 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TAF1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TAF1-20-RE | 20 (40 μL) | 200 μL |  |
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| TAF1-20-GO | 20 (40 μL) | 200 μL |  |
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| TAF1-20-GR | 20 (40 μL) | 200 μL |  |
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| TAF1-20-AQ | 20 (40 μL) | 200 μL |  |
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| TAF1-20-DIG | 20 (40 μL) | 200 μL |  |
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| TAF1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N- and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. Mutations in this gene result in Dystonia 3, torsion, X-linked, a dystonia-parkinsonism disorder. Alternative splicing of this gene results in multiple transcript variants. This gene is part of a complex transcription unit (TAF1/DYT3), wherein some transcript variants share exons with TAF1 as well as additional downstream DYT3 exons. [provided by RefSeq, Oct 2013]
Gene Details
Gene Symbol: TAF1
Gene Name: TATA-box Binding Protein Associated Factor 1
Chromosome: CHRX: 70586113-70685855
Locus: Xq13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BG:DS00004.13 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TAF1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping