BCNS FISH Probe
The BCNS FISH probe is designed to hybridize to the BCNS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTCH1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PTCH1-20-RE | 20 (40 μL) | 200 μL |  |
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| PTCH1-20-GO | 20 (40 μL) | 200 μL |  |
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| PTCH1-20-GR | 20 (40 μL) | 200 μL |  |
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| PTCH1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PTCH1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PTCH1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the patched family of proteins and a component of the hedgehog signaling pathway. Hedgehog signaling is important in embryonic development and tumorigenesis. The encoded protein is the receptor for the secreted hedgehog ligands, which include sonic hedgehog, indian hedgehog and desert hedgehog. Following binding by one of the hedgehog ligands, the encoded protein is trafficked away from the primary cilium, relieving inhibition of the G-protein-coupled receptor smoothened, which results in activation of downstream signaling. Mutations of this gene have been associated with basal cell nevus syndrome and holoprosencephaly. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: PTCH1
Gene Name: Patched 1
Chromosome: CHR9: 98205263-98279247
Locus: 9q22.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: BCNS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTCH1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping