AXIN1-RGS FISH Probe
The AXIN1-RGS FISH probe is designed to hybridize to the AXIN1-RGS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AXIN1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| AXIN1-20-RE | 20 (40 μL) | 200 μL |  |
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| AXIN1-20-GO | 20 (40 μL) | 200 μL |  |
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| AXIN1-20-GR | 20 (40 μL) | 200 μL |  |
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| AXIN1-20-AQ | 20 (40 μL) | 200 μL |  |
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| AXIN1-20-DIG | 20 (40 μL) | 200 μL |  |
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| AXIN1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: AXIN1
Gene Name: Axin 1
Chromosome: CHR16: 337439-402676
Locus: 16p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: AXIN1-RGS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: AXIN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping