ARVD11 FISH Probe
The ARVD11 FISH probe is designed to hybridize to the ARVD11 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
DSC2-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
DSC2-20-RE | 20 (40 μL) | 200 μL | ||
DSC2-20-GO | 20 (40 μL) | 200 μL | ||
DSC2-20-GR | 20 (40 μL) | 200 μL | ||
DSC2-20-AQ | 20 (40 μL) | 200 μL | ||
DSC2-20-DIG | 20 (40 μL) | 200 μL | ||
DSC2-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Gene Details
Gene Symbol: DSC2
Gene Name: Desmocollin 2
Chromosome: CHR18: 28645941-28682388
Locus: 18q12.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ARVD11 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DSC2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping