ARNT FISH Probe
The ARNT FISH probe is designed to hybridize to the ARNT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
ARNT-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
ARNT-20-RE | 20 (40 μL) | 200 μL | ||
ARNT-20-GO | 20 (40 μL) | 200 μL | ||
ARNT-20-GR | 20 (40 μL) | 200 μL | ||
ARNT-20-AQ | 20 (40 μL) | 200 μL | ||
ARNT-20-DIG | 20 (40 μL) | 200 μL | ||
ARNT-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
Gene Details
Gene Symbol: ARNT
Gene Name: Aryl Hydrocarbon Receptor Nuclear Translocator
Chromosome: CHR1: 150782180-150849244
Locus: 1q21.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: ARNT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ARNT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping