APC5 FISH Probe
The APC5 FISH probe is designed to hybridize to the APC5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANAPC5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ANAPC5-20-RE | 20 (40 μL) | 200 μL |  |
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| ANAPC5-20-GO | 20 (40 μL) | 200 μL |  |
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| ANAPC5-20-GR | 20 (40 μL) | 200 μL |  |
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| ANAPC5-20-AQ | 20 (40 μL) | 200 μL |  |
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| ANAPC5-20-DIG | 20 (40 μL) | 200 μL |  |
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| ANAPC5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
Gene Details
Gene Symbol: ANAPC5
Gene Name: Anaphase Promoting Complex Subunit 5
Chromosome: CHR12: 121746047-121792012
Locus: 12q24.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: APC5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ANAPC5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping