APC10 FISH Probe
The APC10 FISH probe is designed to hybridize to the APC10 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ANAPC10-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ANAPC10-20-RE | 20 (40 μL) | 200 μL |  |
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| ANAPC10-20-GO | 20 (40 μL) | 200 μL |  |
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| ANAPC10-20-GR | 20 (40 μL) | 200 μL |  |
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| ANAPC10-20-AQ | 20 (40 μL) | 200 μL |  |
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| ANAPC10-20-DIG | 20 (40 μL) | 200 μL |  |
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| ANAPC10-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).[supplied by OMIM, Feb 2011]
Gene Details
Gene Symbol: ANAPC10
Gene Name: Anaphase Promoting Complex Subunit 10
Chromosome: CHR4: 145916312-146019368
Locus: 4q31.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: APC10 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ANAPC10-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping